CLINICALLY PROVEN BENFITS


After an injury or orthopedic surgery, the rehab and recovery process is critical to successful outcomes. With the Game Ready* GRPro* 2.1 cold and compression therapy system, finish strong and get back to what matters.

HOW THE GAME READY SYSTEM WORKS


The Game Ready* System combines cryotherapy with intermittent compression after injury or surgery.

GRPRO 2.1 CLINICAL BENEFITS


May facilitate a decrease in patient opioid consumption and may allow for earlier discontinuation of opioid medications post-operatively.†

Integrates cold and compression therapies to help reduce pain and edema – outperforming conventional rest, ice, compression, and elevation (RICE) methods.†

May increase patient satisfaction with the postoperative recovery process.†

Studies have shown early discharge when using Game Ready.†

May lead to lower post-operative blood loss.†

MED4 ELITE MODALITY CLINICAL BENEFITS


COLD & ACTIVE COMPRESSION THERAPY


May facilitate a decrease in patient opioid consumption and may allow for earlier discontinuation of opioid medications post-operatively.†

Integrates cold and compression therapies to help reduce pain and edema – outperforming conventional rest, ice, compression, and elevation (RICE) methods.†

May increase patient satisfaction with the postoperative recovery process.†

Studies have shown early discharge when using Game Ready.†

May lead to lower post-operative blood loss.†

HEAT THERAPY


Med4 Elite heat therapy can be used alone or in conjunction with cold for contrast therapy.

CONTRAST THERAPY


The Med4 Elite is capable of a hot-cold changeover rate of less than one minute.

1. Su EP, Perna M, Boettner F, Mayman DJ, Gerlinger T, Barsoum W, Randolph J, Lee G. A prospective, multi-center, randomised trial to evaluate the efficacy of a cryopneumatic device on total knee arthroplasty recovery. The Journal of Bone and Joint Surgery. 2012; 94-B, Supple A:153-6. https://www.ncbi.nlm.nih.gov/pubmed/23118406.
2. Waterman B, Walker JJ, Swains C, Shortt M, Todd MS, Machen SM, Owens BD. The efficacy of combined cryotherapy compression compared with cryotherapy alone following anterior cruciate ligament reconstruction. The Journal of Knee Surgery. 2012; 25, (02):155-160. https://www.ncbi.nlm.nih.gov/pubmed/22928433.
3. Murgier J, Cassard X. Cryotherapy with dynamic intermittent compression for analgesia after anterior cruciate ligament reconstruction. Preliminary study. Orthopaedics & Traumatology: Surgery & Research. 2014; 100:309-312. https://www.ncbi.nlm.nih.gov/pubmed/24679367.
4. Nabıyev VN, Ayhan S, Adhıkarı P, Cetın E, Palaoglu S, Acaroglu RE. Cryo-compression therapy after elective spinal surgery for pain management: a cross-sectional study with historical control. Neurospine. 2018; 15(4):348-352. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347345/pdf/ns-1836070-035.pdf.
5. Bellon M, Michelet D, Carrara N, Vacher T, Gafsou B, Ilhareborde B, Mazda K, Ferrero E, Simon AL, Julien‑Marsollier F, Dahmani S. Efficacy of the Game Ready* cooling device on postoperative analgesia after scoliosis surgery in children. European Spine Journal. 2019; 28:1257–1264. https://link.springer.com/article/10.1007%2Fs00586-019-05886-6.
6. Klaber I, Greeff E, O’Donnell J. Compressive cryotherapy is superior to cryotherapy alone in reducing pain after hip arthroscopy. Journal of Hip Preservation Surgery. 2019; 0(0):1-6. https://academic.oup.com/jhps/advance-article/doi/10.1093/jhps/hnz048/5610188.
7. Murgier J, Cailliez J, Wargny M, Chiron P, Cavaignac E, Laffosse JM. Cryotherapy with dynamic intermittent compression improves recovery from revision total knee arthroplasty. The Journal of Arthroplasty. 2017; 1-4. https://pubmed.ncbi.nlm.nih.gov/28465126.
8. As with all RICE applications.
9. Leegwater NC, Willems JH, Brohet R, Nolte PA. Cryocompression therapy after elective arthroplasty of the hip. Hip International. 2012; 22 (05):527-533. https://www.ncbi.nlm.nih.gov/pubmed/23112075.

There are inherent risks in all medical devices. Please refer to the product labeling for Indications, Cautions, Warnings and Contraindications. Refer to www.gameready.com for product safety technical bulletins.

Game Ready Thermal Imagery Comparison

Game Ready cold shown in thermal imagery


Game Ready wraps provide enhanced anatomical coverage due to their circumferential design. Moreover, Game Ready wraps allow for the coldest skin surface temperature for up to 30 minutes post treatment compared to other devices tested.**

**Thermal images and skin temperatures taken immediately after 30 minutes of treatment, all devices applied per manufacturer’s instructions under identical conditions. Thermal Test Imaging marketing comparison, (Sections 7.0 and 7.1). ETR #2712: Study performed 10/10/19.

CLINICAL STUDY ABSTRACTS


A Prospective, Multi-center, Randomized Trial To Evaluate The Efficacy Of A Cryopneumatic Device On Total Knee Arthroplasty Recovery

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Cryocompression Therapy After Elective Arthroplasty Of The Hip

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The Efficacy Of Combined Cryotherapy And Compression Compared With Cryotherapy Alone Following Anterior Cruciate Ligament Reconstruction

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Cryotherapy With Dynamic Intermittent Compression For Analgesia After Anterior Cruciate Ligament Reconstruction

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Compressive Cryotherapy Is Superior To Cryotherapy Alone In Reducing Pain After Hip Arthroscopy

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Cryo-Compression Therapy After Elective Spinal Surgery For Pain Management: A Cross-Sectional Study With Historical Control

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Efficacy Of The Game Ready® Cooling Device On Postoperative Analgesia After Scoliosis Surgery In Children

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Cryotherapy With Dynamic Intermittent Compression Improves Recovery From Revision Total Knee Arthroplasty

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Andersen P, Gjerstad L, Pasztor E. (1972). Effect of cooling on synaptic transmission through the cuneate nucleus. Acta Physiologica, 84(4), 433-447.

Berliner E, Ozbilgin B, Zarin DA. (2003). A systematic review of pneumatic compression for treatment of chronic venous insufficiency and venous ulcers. Journal of Vascular Surgery, 37(3), 539-544.

Bleakley C, McDonough S, MacAuley D. (2004). The use of ice in the treatment of acute soft-tissue injury a systematic review of randomized controlled trials. The American Journal of Sports Medicine, 32(1), 251-261.

Chleboun GS, Howell JN, Baker HL, Ballard TN, Graham JL, Hallman HL, … Conatser RR. (1995). Intermittent pneumatic compression effect on eccentric exercise-induced swelling, stiffness, and strength loss. Archives of Physical Medicine and Rehabilitation, 76(8), 744-749.

Cochrane DJ. (2004). Alternating hot and cold water immersion for athlete recovery: a review. Physical Therapy in Sport, 5(1), 26-32.

Comerota AJ. (2011). Intermittent pneumatic compression: physiologic and clinical basis to improve management of venous leg ulcers. Journal of Vascular Surgery, 53(4), 1121-1129.

Daanen, HAM. (2003). Finger cold-induced vasodilation: a review. European Journal of Applied Physiology. 89(5):411-426.

Denegar CR, Dougherty DR, Friedman JE, Schimizzi ME, Clark JE, Comstock BA, Kraemer WJ. (2010). Preferences for heat, cold, or contrast in patients with knee osteoarthritis affect treatment response. Clinical Interventions in Aging, 5, 199.

Flandry F, Hunt JP, Terry GC, Hughston JC. (1991). Analysis of subjective knee complaints using visual analog scales. The American Journal of Sports Medicine, 19(2), 112-118.

Hayes KW. (1993). Heat and cold in the management of rheumatoid arthritis. Arthritis & Rheumatology, 6(3), 156-166.

Hubbard TJ, Denegar CR. (2004). Does cryotherapy improve outcomes with soft tissue? Journal of Athletic Training, 39(3):278-79.

Ingraham P. (Nov. 2015). Contrast hydrotherapy. Pain Science. Retrieved from https://www.painscience.com/articles/contrasting.php.

Johansson K, Lie E, Ekdahl C, Lindfeldt J. (1998). A randomized study comparing manual lymph drainage with sequential pneumatic compression for treatment of postoperative arm lymphedema. Lymphology, 31(2):56-64.

Knight KL. (1995). Cryotherapy in sport injury management. Human Kinetics. Champaign, IL.

Kottke FJ, Lehmann JF. (1990). Handbook of Physical Medicine and Rehabilitation. W.B. Saunders Company, Philadelphia, PA.

Kowal MA. (1983). Review of physiological effects of cryotherapy. Journal of Orthopaedic & Sports Physical Therapy, 5(2), 66-73.

Kraemer WJ, Bush JA, Wickham RB, Denegar CR, Gómez AL, Gotshalk LA, … Sebastianelli WJ. (2001). Influence of compression therapy on symptoms following soft tissue injury from maximal eccentric exercise. Journal of Orthopaedic & Sports Physical Therapy, 31(6), 282-290.

Mayer JM, Mooney V, Matheson LN, Erasala GN, Verna JL, Udermann BE, Leggett S. (2006). Continuous low-level heat wrap therapy for the prevention and early phase treatment of delayed-onset muscle soreness of the low back: a randomized controlled trial. Archives of Physical Medicine and Rehabilitation, 87(10), 1310-1317.

Myrer JW, Draper DO, Durrant E. (1994). Contrast therapy and intramuscular temperature in the human leg. Journal of Athletic Training, 29(4), 318-322.

Prentice WE, Quillen WS, Underwood FB. (1998). Therapeutic Modalities for Allied Health Professionals. McGraw-Hill Health Professions Division, New York.

Starkey C. Therapeutic Modalities for Athletic Trainers. Philadelphia: FA Davis, 1999.

Stillwell GK. (1987). Therapeutic heat and cold. Handbook of Physical Medicine and Rehabilitation, Ed. 2.

Study Group 5 (2007). Clinical evaluation (appendix D: a possible method of appraisal). Global Harmonization Task Force. N2R8. Retrieved on 3/9/2017 from http://www.imdrf.org/docs/ghtf/final/sg5/technical-docs/ghtf-sg5-n2r8-2007-clinical-evaluation-070501.pdf.

Trowbridge CA, Womochel KS, Davis DR. (2008) The effects of continuous cooling and cyclical compression on intramuscular and surface temperatures of the distal quadriceps. Journal of Athletic Training, 43(3):s58.

Wilkerson GB. (1991). Treatment of the inversion ankle sprain through synchronous application of focal compression and cold. Journal of Athletic Training, 26:220-36.

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Zeigler T. (2016). Using thermotherapy to treat sports injuries. Sports MD. Retrieved from http://www.sportsmd.com/injury-recovery/using-thermotherapy-treat-sports-injuries.

1. Su EP, Perna M, Boettner F, Mayman DJ, Gerlinger T, Barsoum W, Randolph J, Lee G. A prospective, multi-center, randomised trial to evaluate the efficacy of a cryopneumatic device on total knee arthroplasty recovery. The Journal of Bone and Joint Surgery. 2012; 94-B, Supple A:153-6. https://www.ncbi.nlm.nih.gov/pubmed/23118406.
2. Waterman B, Walker JJ, Swains C, Shortt M, Todd MS, Machen SM, Owens BD. The efficacy of combined cryotherapy compression compared with cryotherapy alone following anterior cruciate ligament reconstruction. The Journal of Knee Surgery. 2012; 25, (02):155-160. https://www.ncbi.nlm.nih.gov/pubmed/22928433.
3. Murgier J, Cassard X. Cryotherapy with dynamic intermittent compression for analgesia after anterior cruciate ligament reconstruction. Preliminary study. Orthopaedics & Traumatology: Surgery & Research. 2014; 100:309-312. https://www.ncbi.nlm.nih.gov/pubmed/24679367.
4. Nabıyev VN, Ayhan S, Adhıkarı P, Cetın E, Palaoglu S, Acaroglu RE. Cryo-compression therapy after elective spinal surgery for pain management: a cross-sectional study with historical control. Neurospine. 2018; 15(4):348-352. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347345/pdf/ns-1836070-035.pdf.
5. Bellon M, Michelet D, Carrara N, Vacher T, Gafsou B, Ilhareborde B, Mazda K, Ferrero E, Simon AL, Julien‑Marsollier F, Dahmani S. Efficacy of the Game Ready* cooling device on postoperative analgesia after scoliosis surgery in children. European Spine Journal. 2019; 28:1257–1264. https://link.springer.com/article/10.1007%2Fs00586-019-05886-6.
6. Klaber I, Greeff E, O’Donnell J. Compressive cryotherapy is superior to cryotherapy alone in reducing pain after hip arthroscopy. Journal of Hip Preservation Surgery. 2019; 0(0):1-6. https://academic.oup.com/jhps/advance-article/doi/10.1093/jhps/hnz048/5610188.
7. Murgier J, Cailliez J, Wargny M, Chiron P, Cavaignac E, Laffosse JM. Cryotherapy with dynamic intermittent compression improves recovery from revision total knee arthroplasty. The Journal of Arthroplasty. 2017; 1-4. https://pubmed.ncbi.nlm.nih.gov/28465126.
8. As with all RICE applications.
9. Leegwater NC, Willems JH, Brohet R, Nolte PA. Cryocompression therapy after elective arthroplasty of the hip. Hip International. 2012; 22 (05):527-533. https://www.ncbi.nlm.nih.gov/pubmed/23112075.

There are inherent risks in all medical devices. Please refer to the product labeling for Indications, Cautions, Warnings and Contraindications. Refer to www.gameready.com for product safety technical bulletins.

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